Local tumor therapy with balloon catheter
subproject 3 – MRI-guided Local Cancer Treatment Using Coated Balloon Catheters
Radiological interventions are an alternative to the surgical removal of a tumor. Such interventions are minimally invasive procedures that require image-guided insertion of a catheter into the body. The catheters serve to introduce a laser or radiation source for local cancer treatment into any part of the body.
Local drug delivery using coated balloons is a novel approach for restoring sustained patency of narrowed vessels. A catheter with a small balloon on which the drug has been coated is advanced into the narrowed vessel segment and then inflated to deliver high concentrations of the drug at the site of narrowing. In this way, the diseased tissue is exposed to high concentrations of the drug, while adverse effects on normal tissue are minimized.
The aim of this subproject is to develop and establish a technique for balloon catheter placement in liver tumors under MRI guidance. The greatest technical challenge of this endeavor is to accurately localize the catheter by means of MRI. Our research focuses on the identification of a highly integrated, interactive method that is also applicable to other instruments.
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